Since Modafinil and Adrafinil are closely related stimulants, many people would be wondering, “How does Adrafinil compare to Modafinil.” Well, this article will answer this question in its entirety. Adrafinil and Modafinil are popular modern nootropics because they help to give brainpower as well as boost and banish sleepiness and fatigue temporarily.
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These two substances are related and produce virtually the same effects, but they are also different in various ways. Adrafinil is more like Modafinil but without the sweats.


  • This is the one that has the active effects of increasing your energy, wakefulness, memory, and focus. In most countries, however, Modafinil is usually prescribed as narcolepsy which is the disorder that causes you to fall asleep during the daytime.
  • Because of its nootropics effects and is also registered and used as medicine it is difficult to Modafinil without a prescription from the doctor.


  • When someone takes Adrafinil, it gets converted to Modafinil in the body. Unlike Modafinil, Adrafinil can be bought legally without a prescription since it’s not a prescription drug.
  • Because Adrafinil needs to be converted to Modafinil in your body once you take it, it takes a more extended period to become active and start working in your body. Once it starts to work inside your body, it has the same effects.

Similarities of Adrafinil and Modafinil

  • Once you ingest Adrafinil, it gets metabolized in the liver where it gets converted into the active Modafinil, and the remainder is gets metabolized to the inactive modafinil acid. Both of these drugs have the same action in mechanisms as well as benefits and effects.
  • Both of these drugs help to increase the output of the brain’s hypocretin system in the brain by activating neurons in the amygdala and hypothalamus. This is mainly responsible for wakefulness, contributes to alertness, and also helps to increase the availability of glutamate which is an important excitatory neurotransmitter which is crucial to general cognition, memory, and also executive function.
  • This then increases a person’s productivity in their daily activities, thereby increasing their happiness and improving their life quality. A person can provide for their loved ones without serious interruptions brought about by fatigue and sleepiness in their daily hustle.
  • A combo of Adrafinil and Modafinil also help to increase the amount of dopamine that is available in the brain. Since dopamine is a neurotransmitter that helps to create reward response or pleasure, increasing its availability is quite helpful in improving alertness and elevating mood. This then keeps someone happy and comfortable as they go about their day to day activities.
  • The good thing about both Adrafinil and Modafinil is that they are considered to have less addictive potential as compared to other stimulants because they have an indirect effect on the dopaminergic system. This is reassuring, and anyone can comfortably use them to enhance better quality of life.

Effects and Benefits of Adrafinil vs. Modafinil

Here, we’ll get to discuss some of the impact as well as benefits that come about from using Adrafinil and Modafinil.

Effects and Benefits

  • Both Modafinil and Adrafinil help to promote wakefulness, increase alertness, delay the onset of fatigue, reduce tiredness and perception, and also inhibit the drive to sleep.
  • Research has shown that eugeroics are more effective compared to methamphetamine when it comes to inhibiting the urge to sleep. They help to produce consolidated periods of wakefulness.
  •  Although, both Modafinil and Adrafinil are effective and safe to use, to worth noting that long-term use of these drugs is not recommended.
  • Both Adrafinil and Modafinil have shown to create a significant improvement in a wide range of cognitive abilities. This ranges from the increase in working memory, episodic memory, fluid intelligence, executive function, pattern recognition, as well as other performance tasks which require a high level of thinking.


Although both Modafinil and Adrafinil can be said to be almost similar, they do tend to have a bit of difference. Let’s take a closer look at some of these differences.

    • Adrafinil is less potent compared to Modafinil; therefore Modafinil requires lower doses to have the same level of effectiveness of Adrafinil. This difference comes about because not all Adrafinil gets converted to Modafinil when ingested by a patient.
    • Another difference between the two drugs is that Adrafinil has more toxic potential, unlike Modafinil. This is because it has to be metabolized in the liver once taken. However, the toxicity can be as a result of long-term daily usage.
    • When it comes to the effects of the two drugs once taken by a patient, they also tend to differ in various ways. Modafinil acts faster than Adrafinil. Also, Modafinil peaks between 60 to 90 minutes while Adrafinil can take another hour to the peak.

  • In terms of cost, Modafinil is more expensive than Adrafinil.
  • The legal status between the two drugs also differs from country to country. Although the World Anti-Doping Association banned the use of both Adrafinil and Modafinil, in most countries you can buy Adrafinil without any prescription.
  • These two stimulants are highly effective at ensuring that a person can sustain their wakefulness, keeping alert as well as ensuring that they slow the effects of tiredness. They are popular with people who have careers with shifts that do not provide for regular sleeping hours, whereas this interruption may cause someone to sleep on the job.
  • Unlike other stimulants available in the market, these two are amazing at ensuring that someone does not get to have excessive sleep when they stop taking them. This is a significant advantage of both Adrafinil and Modafinil, thereby easily making them the stimulant of choice for many people.
  • However, it is essential that whenever someone decides to take either of these two, they understand the right dosage to use for the purpose they intend to accomplish.
  • Overdosing either of the two is not desirable and could cause more problems than what they are solving. Getting a prescription from a physician is the best bet for any person as they would guide as to how best to take them.